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Leber Hereditary Optic Neuropathy - 21 Studies Found

Status Study
Recruiting Study Name: Safety and Efficacy Study of Gene Therapy for The Treatment of Leber's Hereditary Optic Neuropathy
Condition: Leber Hereditary Optic Neuropathy
Date: 2017-05-10
Interventions:
  • Drug: rAAV2-ND4 a Single IVT I
Completed Study Name: Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON)
Condition: Leber Hereditary Optic Neuropathy
Date: 2010-12-27
Interventions: Drug: rAAV2-ND4 injection Other Name: rAAV2-ND4 gene
Completed Study Name: Study to Assess Efficacy,Safety and Tolerability of Idebenone in the Treatment of Leber's Hereditary Optic Neuropathy
Condition: Leber's Hereditary Optic Neuropathy
Date: 2008-09-04
Interventions:
  • Drug: Idebenone Idebenone 900

No longer available Study Name: Emergency Administration of EPI-743 to a Single Patient With Leber's Hereditary Optic Neuropathy [LHON]
Condition: Leber's Hereditary Optic Neuropathy
Date: 2014-11-21
Interventions: Drug: EPI-743 EPI-743 is a quinone oxidation product of alpha-tocotrienol
Active, not recruiting Study Name: Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients
Condition: Leber Hereditary Optic Neuropathy
Date: 2014-02-13
Interventions: Genetic: GS010
Recruiting Study Name: Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy
Condition: Leber's Hereditary Optic Neuropathy
Date: 2014-06-06
Interventions:
  • Drug: injection of scAAV2-P1ND4v2 5.00x10e9 vg (Low),

Active, not recruiting Study Name: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide (MTP-131) Topical Ophthalmic Solution for the Treatment of Leber's Hereditary Optic Neuropathy
Condition: Leber's Hereditary Optic Neuropathy
Date: 2016-02-15
Interventions:
  • Drug: elamipretide (MTP-131) 1% topical ophthalmic solution
Terminated Study Name: Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)
Condition: Leber's Hereditary Optic Neuropathy (LHON)
Date: 2011-07-06
Interventions: Device: Near-infrared light-emitting diode (NIR-LED) therapy (Med Light 630 PRO (Medical Devices Inc.))
Recruiting Study Name: Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)
Condition: Leber's Hereditary Optic Neuropathy (LHON)
Date: 2016-06-07
Completed Study Name: RHODOS Follow-up Single-visit Study
Condition: Leber's Hereditary Optic Neuropathy
Date: 2011-08-19
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