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Optic Atrophies, Hereditary - 25 Studies Found

Status Study
Completed Study Name: A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)
Condition: Optic Atrophy, Hereditary, Leber
Date: 2007-09-11
Interventions: Drug: curcumin curcumin 250 mg twice a day in the first group. placebo 1 capsule twice a day in the seco
Recruiting Study Name: Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)
Condition: Leber's Hereditary Optic Neuropathy (LHON)
Date: 2016-06-07
Recruiting Study Name: Study to Assess the Efficacy and Safety of Raxone in LHON Patients
Condition: Leber's Hereditary Optic Neuropathy (LHON)
Date: 2016-05-12
Interventions: Drug: Idebenone Other Name: Raxone
Recruiting Study Name: Post Authorisation Safety Study With Raxone in LHON Patients
Condition: Leber's Hereditary Optic Neuropathy (LHON)
Date: 2016-04-25
Interventions: Drug: Idebenone Raxone 900mg/day as per Raxone SmPC and medical judgement of treating physician.
Active, not recruiting Study Name: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide (MTP-131) Topical Ophthalmic Solution for the Treatment of Leber's Hereditary Optic Neuropathy
Condition: Leber's Hereditary Optic Neuropathy
Date: 2016-02-15
Interventions:
  • Drug: elamipretide (MTP-131) 1% topical ophthalmic solution
Active, not recruiting Study Name: Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy
Condition: Leber Hereditary Optic Neuropathy
Date: 2014-06-25
Interventions: Drug: cyclosporine
Recruiting Study Name: Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy
Condition: Leber's Hereditary Optic Neuropathy
Date: 2014-06-06
Interventions:
  • Drug: injection of scAAV2-P1ND4v2 5.00x10e9 vg (Low),

Active, not recruiting Study Name: Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients
Condition: Leber Hereditary Optic Neuropathy
Date: 2014-02-13
Interventions: Genetic: GS010
Completed Study Name: Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey
Condition: Leber Hereditary Optic Neuropathy (LHON)
Date: 2013-06-26
Withdrawn Study Name: Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)
Condition: Leber's Hereditary Optic Neuropathy
Date: 2011-12-16
Interventions:
  • Drug: Idebenone
  • Drug: Placebo
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