Symptoms of depression can vary from person to person. Key signs and symptoms may include: Depression that temporarily lifts in response to good news or positive events Increased appetite that can cause weight gain Increased desire to sleep, usually more than 10 hours a day Heavy, leaden feeling in your arms or legs that lasts an hour or more in a day — a feeling that is different from fatigue  Read More

Marinesco-Sjögren Syndrome (MSS) is an autoimmune disease that causes the body to attack its own nerves. It is a rare disorder that affects both the nervous and immune systems. It is sometimes called "double-hit" because it's caused by two separate genetic mutations. The first mutation activates an inactive protein in the cell, which causes inflammation and damage to the nerves. The second mutation prevents the body from maki  Read More

Migraine headache is a result of specific changes within the brain. It causes severe head pain that is often accompanied by sensitivity to light, sound, or smells. Common symptoms of migraine are: Eye pain Sensitivity to light or sound Nausea Vomiting Severe pain, usually on one side of the head that some individuals describe as "pounding" Other types of  Read More

De Sanctis-Cacchione syndrome is an extremely rare disorder characterized by the skin and eye symptoms of xeroderma pigmentosum (XP) occurring in association with neurological abnormalities, mental retardation, unusually short stature (dwarfism), and underdevelopment of the testes or ovaries (hypogonadism). Xeroderma pigmentosum is a group of rare inherited skin disorders characterized by a heightened reaction to ultraviolet light (photosensit  Read More